DROSOPHILA AND GENOME-WIDE ASSOCIATION STUDIES: A REVIEW AND RESOURCE FOR THE FUNCTIONAL DISSECTION OF HUMAN COMPLEX TRAITS

Drosophila and genome-wide association studies: a review and resource for the functional dissection of human complex traits

Human genome-wide association studies (GWAS) have successfully identified thousands of susceptibility loci for common diseases with complex genetic etiologies.Although the susceptibility variants identified by GWAS usually have only modest effects on individual disease risk, they contribute to a substantial burden of trait variation in the overall

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Data on neurophysiological and psychological responses to audio immersive experience in stereo and 3D audio formats

Abstract Objectives This dataset presents demographic, psychological, auditory and neurophysiological information of 31 volunteers, who participated in an experiment measuring the auditory immersive experience in two audio formats: stereophonic downmix and three-dimensional audio.This dataset could help understand the objectiveness (based on the ne

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Short linear motif acquisition, exon formation and alternative splicing determine a pathway to diversity for NCoR-family co-repressors

Vertebrate NCoR-family co-repressors play central roles in the timing of embryo and stem cell differentiation by repressing the activity of a range of transcription factors.They interact with nuclear receptors using short linear motifs (SLiMs) termed co-repressor for nuclear receptor (CoRNR) boxes.Here, we identify the pathway leading to increasing

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